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Sanofi, a diversified global healthcare leader, discovers, develops, and distributes therapeutic solutions to improve the lives of everyone. We work to prevent and treat the diseases that we know of today, as well as those we may face tomorrow. With nearly 100,000 dedicated professionals in more than 100 countries, Sanofi is devoted to advancing healthcare around the world. Sanofi US, with headquarters in Bridgewater, New Jersey, along with our vaccines division, Sanofi Pasteur, employs more than 11,400 professionals throughout the country. At Sanofi, we work for what really matters: health
Translational Medicine bioinformatics analyst. We seek an experienced bioinformatics scientist / computational biologist to join a dynamic Translational Medicine bioinformatics group dedicated to the development of cancer therapeutics.
As an integrated part of a Translational and Experimental Medicine and Target Discovery teams identifying the biological context in which targeted cancer therapies can be effective, you will:
• Develop analysis and quality control pipelines for a variety of Next Generation Sequencing (NGS) applications such as DNA-seq, ChIP-seq, and RNA-seq
• Develop novel statistical methods for indel, SNP, genotype, fusion and complex variant calling on a variety of internal and external sequencing platforms (454, SOLID, Illumina, PacBIO, etc.)
• Design the strategy for sequencing outsourcing as well as sequencing workflow data management and the computing infrastructure for processing NGS data (local vs. Amazon cloud, etc.)
• Develop Translational Medicine plans (e.g., patient selection and indication biomarkers) in collaboration with Translational and Experimental Medicine project teams
• Supply any computational, statistical, machine learning or modeling capability needed to synthesize data into the actionable next steps for the Projects
Requirements :
Educational requirements
• Ph.D. in a computational, statistical, biophysics, or bioinformatics related fields
• A minimum of 5-years research (academia or industry) experience
Knowledge requirements
An ideal candidate will be collaborative, self-directed and possess
• First-hand experience in NGS analysis, methods, and data management
• First-hand multi-parametric data mining experience on expression, copy number and profiling datasets for target identification and biomarker discovery. For example, multivariate analysis; dimensionality reduction methods; parametric and non-parametric statistical methods; Bayesian statistics; pattern recognition or classification methods.
• First-hand experience at integrating publicly or commercially available genetic, genomic, and interaction datasets with novel experimental data to identify testable hypotheses
• Statistical programming skills like SAS/S-plus, R/bioconductor and pipeline pilot or equivalents
• A background in Oncology, Translational Research, Pathway Analysis, Quantitative Methods for Systems Biology, Network Analysis, or Simulation are a plus.
Required Key Attributes
• Positive, proactive can-do mindset
• Demonstrated ability to lead projects of moderate scope, mapping-out critical path, milestones and timelines, as well as manage customer expectations with minimal supervision
• Developed communication and presentation skills and a successful track record of collaborating with cross-functional scientific teams
Please apply online at: http://www.sanofi.us/l/us/en/layout....7-EE9BFE683320 R&D17043
Translational Medicine bioinformatics analyst. We seek an experienced bioinformatics scientist / computational biologist to join a dynamic Translational Medicine bioinformatics group dedicated to the development of cancer therapeutics.
As an integrated part of a Translational and Experimental Medicine and Target Discovery teams identifying the biological context in which targeted cancer therapies can be effective, you will:
• Develop analysis and quality control pipelines for a variety of Next Generation Sequencing (NGS) applications such as DNA-seq, ChIP-seq, and RNA-seq
• Develop novel statistical methods for indel, SNP, genotype, fusion and complex variant calling on a variety of internal and external sequencing platforms (454, SOLID, Illumina, PacBIO, etc.)
• Design the strategy for sequencing outsourcing as well as sequencing workflow data management and the computing infrastructure for processing NGS data (local vs. Amazon cloud, etc.)
• Develop Translational Medicine plans (e.g., patient selection and indication biomarkers) in collaboration with Translational and Experimental Medicine project teams
• Supply any computational, statistical, machine learning or modeling capability needed to synthesize data into the actionable next steps for the Projects
Requirements :
Educational requirements
• Ph.D. in a computational, statistical, biophysics, or bioinformatics related fields
• A minimum of 5-years research (academia or industry) experience
Knowledge requirements
An ideal candidate will be collaborative, self-directed and possess
• First-hand experience in NGS analysis, methods, and data management
• First-hand multi-parametric data mining experience on expression, copy number and profiling datasets for target identification and biomarker discovery. For example, multivariate analysis; dimensionality reduction methods; parametric and non-parametric statistical methods; Bayesian statistics; pattern recognition or classification methods.
• First-hand experience at integrating publicly or commercially available genetic, genomic, and interaction datasets with novel experimental data to identify testable hypotheses
• Statistical programming skills like SAS/S-plus, R/bioconductor and pipeline pilot or equivalents
• A background in Oncology, Translational Research, Pathway Analysis, Quantitative Methods for Systems Biology, Network Analysis, or Simulation are a plus.
Required Key Attributes
• Positive, proactive can-do mindset
• Demonstrated ability to lead projects of moderate scope, mapping-out critical path, milestones and timelines, as well as manage customer expectations with minimal supervision
• Developed communication and presentation skills and a successful track record of collaborating with cross-functional scientific teams
Please apply online at: http://www.sanofi.us/l/us/en/layout....7-EE9BFE683320 R&D17043