Hello,
I was wondering if anybody knows whether or the degree to which removing the low quality ends of Illumina reads (100x2 paired end) will improve denovo assembly? When asking my colleagues as to whether I should "clean" my data by first quality trimming it, I've gotten mixed responses and I haven't come across any papers addressing this. Thoughts?
Thanks!
I was wondering if anybody knows whether or the degree to which removing the low quality ends of Illumina reads (100x2 paired end) will improve denovo assembly? When asking my colleagues as to whether I should "clean" my data by first quality trimming it, I've gotten mixed responses and I haven't come across any papers addressing this. Thoughts?
Thanks!
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