I still receive a fair number of PMs and emails in response to this posting which means people are interested in a tool that converts a FASTA formatted file along with a read alignment file from ELAND or similar to ACE for viewing with Eagleview. I am releasing the script I wrote as source code for anyone to tinker with as a sourceforge project. Feel free to make it more usable. There are issues with the script as it is which I can describe in more detail if people are interested.
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by seqadmin
The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist on Modified Bases...-
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Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...-
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04-04-2024, 04:25 PM -
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