Go Back   SEQanswers > Literature Watch

Similar Threads
Thread Thread Starter Forum Replies Last Post
PubMed: De novo DNA synthesis using single-molecule PCR. Newsbot! Literature Watch 0 02-14-2012 04:00 AM
PubMed: The properties and applications of single-molecule DNA sequencing. Newsbot! Literature Watch 0 02-26-2011 03:20 AM
PubMed: Single-molecule DNA analysis. Newsbot! Literature Watch 0 07-20-2010 02:00 AM
PubMed: Optical Recognition of Converted DNA Nucleotides for Single-Molecule DNA Sequ Newsbot! Literature Watch 0 05-13-2010 02:00 AM

Thread Tools
Old 12-12-2012, 02:00 AM   #1
RSS Posting Maniac

Join Date: Feb 2008
Posts: 1,443
Default PubMed: Single-molecule, genome-scale analyses of DNA modifications: exposing the epi

Syndicated from PubMed RSS Feeds

Related Articles Single-molecule, genome-scale analyses of DNA modifications: exposing the epigenome with next-generation technologies.

Epigenomics. 2012 Aug;4(4):403-14

Authors: Zillner K, Németh A

DNA modifications represent an integral part of the epigenome and they have a pivotal role in regulation of genome function. Despite the wide variety of analytical techniques that have been developed to detect DNA modifications, their investigation at the single-genome level is only beginning to emerge. In contrast to population-averaged analyses, single-molecule approaches potentially allow the mapping of epigenetic linkage between distantly located genomic regions, the locus-specific analysis of repetitive DNA elements, as well as determination of allele-specific DNA modification patterns. In this article, the properties of current single-molecule analyses of DNA modifications will be discussed and compared. In addition, the possible biomedical and discovery research applications of single-molecule epigenomics will be highlighted.

PMID: 22920180 [PubMed - indexed for MEDLINE]

Newsbot! is offline   Reply With Quote

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

All times are GMT -8. The time now is 11:43 PM.

Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO