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  • Hybrid selection

    What's going on in developments for hybrid selection? The Nimblegen/454 approach is one way, but a very expensive way. I visited Agilent when they talked about their removable oligos until they realized that would cut out their market share since you could make infinite amounts once they were stripped (with universal primers).

    Also, if you try to use hybrid selection and then go to one of the short read sequencing platforms you will have real problems of loss of sequence real estate.

    Is anyone out there working on this? Any help and advice would be greatly appreciated.

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  • seqadmin
    Strategies for Sequencing Challenging Samples
    by seqadmin


    Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...
    03-22-2024, 06:39 AM
  • seqadmin
    Techniques and Challenges in Conservation Genomics
    by seqadmin



    The field of conservation genomics centers on applying genomics technologies in support of conservation efforts and the preservation of biodiversity. This article features interviews with two researchers who showcase their innovative work and highlight the current state and future of conservation genomics.

    Avian Conservation
    Matthew DeSaix, a recent doctoral graduate from Kristen Ruegg’s lab at The University of Colorado, shared that most of his research...
    03-08-2024, 10:41 AM

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