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Old 05-25-2010, 01:01 AM   #1
Junior Member
Location: Haifa, Israel

Join Date: Feb 2010
Posts: 4
Default Designing de-novo sequencing projects

Hi everyone.

I was wondering whether anyone is familiar with any paper(s) discussing the design of de-novo sequencing projects and the expected outcome. I mean: what insert sizes do I need, how many inserts from each size, how many contigs and scaffolds are expected (at least in theory, something like the Lander-Waterman model) etc. We plan to sequence a long genome (~120mbp) on a GAIIx machine, but the question is also general.

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