Hello,
I would like to create incorporate a list of 5 million single base variants (SNVs) into an existing reference sequence resulting in a new reference that would match my genome of interest. Alternatively, I could focus on coding regions and incorporate my SNV list into the mRNA of annotated genes.
Does anyone know of a good method to complete either of these?
Thanks
I would like to create incorporate a list of 5 million single base variants (SNVs) into an existing reference sequence resulting in a new reference that would match my genome of interest. Alternatively, I could focus on coding regions and incorporate my SNV list into the mRNA of annotated genes.
Does anyone know of a good method to complete either of these?
Thanks