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  • Bioinformatics Scientist Harvard University

    Bioinformatics Scientist 41334BR

    The Mango Lab in the Harvard Department of Molecular and Cellular Biology in collaboration with the FAS Informatics Group seek a bioinformatician for genomics analysis. The successful candidate will primarily focus their work on the Mango lab, while embedded within a cohort of informaticians who develop and apply cutting edge approaches to a range of biological questions. Current projects within the Mango lab use genomics to study transcriptional regulation and chromatin dynamics during development. ChIP-seq, FAIRE-seq, RNA-seq, Oligopaint etc. are used to probe the chromatin landscape as cells transition from pluripotency to cell-fate commitment, and the successful candidate will collaborate with lab members to analyze the datasets. The remaining effort will be used to support groups in the Faculty of Arts and Sciences (FAS) that use genomic approaches such as ATAC-seq, Chip-seq, FAIRE-seq, and related methodologies. This will include consulting with faculty groups, teaching workshops on statistical and informatics approaches for understanding these methods, and developing best practice recommendations and benchmarks.

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  • seqadmin
    Recent Advances in Sequencing Analysis Tools
    by seqadmin


    The sequencing world is rapidly changing due to declining costs, enhanced accuracies, and the advent of newer, cutting-edge instruments. Equally important to these developments are improvements in sequencing analysis, a process that converts vast amounts of raw data into a comprehensible and meaningful form. This complex task requires expertise and the right analysis tools. In this article, we highlight the progress and innovation in sequencing analysis by reviewing several of the...
    Today, 07:48 AM
  • seqadmin
    Essential Discoveries and Tools in Epitranscriptomics
    by seqadmin




    The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...
    04-22-2024, 07:01 AM

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