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  • Customize removal of unwanted transcripts from RNA-Seq libraries

    Customizable Strand-specific RNA-Seq for Depletion of Unwanted Transcripts from a Broad Range of Species - NuGEN's Insert Dependent Adaptor Cleavage (InDA-C) technology enables depletion of unwanted transcripts through sequence-specific targeting and degradation. The method can be applied to a broad range of transcript types (rRNA, globin, structural protein transcripts, and other housekeeping genes) thereby enriching for more informative transcript sequences in the final library.

    In addition to our products that utilize InDA-C to deplete unwanted transcripts in human blood and FFPE samples (http://www.nugeninc.com/nugen/index....on/human-ffpe/), NuGEN now offer a no cost design service for the selection of InDA-C primers for your transcripts of interest. For further information on how InDA-C methodology can be customized for your project needs please contact NuGEN Technical Support at [email protected]

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  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM
  • seqadmin
    Strategies for Sequencing Challenging Samples
    by seqadmin


    Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...
    03-22-2024, 06:39 AM

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