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  • Customize removal of unwanted transcripts from RNA-Seq libraries

    Customizable Strand-specific RNA-Seq for Depletion of Unwanted Transcripts from a Broad Range of Species - NuGEN's Insert Dependent Adaptor Cleavage (InDA-C) technology enables depletion of unwanted transcripts through sequence-specific targeting and degradation. The method can be applied to a broad range of transcript types (rRNA, globin, structural protein transcripts, and other housekeeping genes) thereby enriching for more informative transcript sequences in the final library.

    In addition to our products that utilize InDA-C to deplete unwanted transcripts in human blood and FFPE samples (http://www.nugeninc.com/nugen/index....on/human-ffpe/), NuGEN now offer a no cost design service for the selection of InDA-C primers for your transcripts of interest. For further information on how InDA-C methodology can be customized for your project needs please contact NuGEN Technical Support at [email protected]

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  • seqadmin
    Essential Discoveries and Tools in Epitranscriptomics
    by seqadmin




    The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...
    04-22-2024, 07:01 AM
  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM

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