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  • In Sequence: Sean Grimmond On Using SOLiD To Study Transcriptomes In Depth

    Syndicated from In Sequence RSS Feed

    Last fall, Sean Grimmond, founder of the Expression Genomic Laboratory at the Institute for Molecular Bioscience at the University of Queensland in Australia, received one of the first Applied Biosystems SOLiD sequencers. In May, Grimmond’s team and ABI scientists published a paper showing how they used the tool to profile stem cell transcriptomes.

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  • seqadmin
    Essential Discoveries and Tools in Epitranscriptomics
    by seqadmin




    The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...
    04-22-2024, 07:01 AM
  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM

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