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01-08-2016, 08:56 AM
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#1 |
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Member
Location: Seattle Join Date: Mar 2008
Posts: 29
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How many missense/nonsense per coding Mb?
what is average number of missense/nonsense per Mb of coding DNA? I found 500 variants/Mb but that includes also synonimous.
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01-08-2016, 09:22 AM
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#2 |
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Senior Member
Location: East Coast USA Join Date: Feb 2008
Posts: 7,091
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Please don't post the same question in multiple forums. That may not necessarily increase your chances of getting an answer.
As for your question: That is going to be dependent on the genome etc. I don't think there can be a single answer. Last edited by GenoMax; 01-08-2016 at 09:24 AM. |
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01-08-2016, 12:38 PM
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#3 | |
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Rick Westerman
Location: Purdue University, Indiana, USA Join Date: Jun 2008
Posts: 1,104
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Quote:
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01-08-2016, 03:17 PM
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#4 |
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Member
Location: Seattle Join Date: Mar 2008
Posts: 29
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I am looking for average in human genomes, could not find info on exomes papers
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04-18-2016, 12:30 AM
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#5 |
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Member
Location: Sweden Join Date: Nov 2009
Posts: 23
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For the human genome I use 1/100 in the non-coding regions and 1/1000 in the coding regions. Per individual of course. This tends to be roughly true. But it will differ between non coding regions and between genes.
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