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DRAGEN Bio-IT processor GenoMax Bioinformatics 2 01-14-2015 08:41 AM

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Old 12-13-2017, 09:02 AM   #1
GERALD
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Location: San Francisco, CA

Join Date: Jun 2010
Posts: 20
Default Dragen

When I first heard about Dragen, it sounded interesting but recently Edico has started to make this platform available on AWS, as well as several Bioinformatics-as-a-service platforms, including DNANexus, Seven Bridges and Illumina's BaseSpace:
http://edicogenome.com/dragen-in-the-cloud/

I think we should all be taking a hard look at this for a couple of reasons:
  • These platforms bring it to a wide audience and make it user-friendly
  • Platform effects: It's a hardware platform with inherent limits on configurability. This will tend to drive users to stadardize on it and effectively freeze pipelines to this standard.
  • It's not available on all platforms.
  • It's really fast!

Based on this, I think it's something to discuss because it's going to have a big impact on the industry.
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Old 01-18-2018, 03:47 AM   #2
colindaven
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Location: Germany

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Default

You forgot the main arguments against DRAGEN

-licenses are limited by throughput
-licenses are REALLY expensive
-licenses are limited by application (buy DNA-seq, can't do RNA-seq).
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fpga, illumina, pipeline

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