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  • Hello from Wisconsin

    Hiya folks, I'm new to computational biology, got a gig doing analysis for Kathy Barton in the Department of Plant Biology at the Carnegie Institution for Science in Stanford, although I live in Madison, Wisconsin. I'm a plasma physicist, and currently teach elementary physics at the UW-Madison as a lecturer when they need me, as well as owning a web app company (IMS) here in Madison where I do a lot of Java programming. I left experimental physics research in 1998.

    You may have seen me if you were at the Cold Spring Harbor Lab conference on Gene Informatics a couple weeks ago.

    Right now I'm working on a bunch of RNA-Seq data (Otogenetics/DNANexus) as well as some older microarray data on similar samples. This is Arabidopsis thaliana, of course.
    Sam Hokin
    Computational Scientist, Carnegie and NCGR

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  • seqadmin
    Current Approaches to Protein Sequencing
    by seqadmin


    Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...
    04-04-2024, 04:25 PM
  • seqadmin
    Strategies for Sequencing Challenging Samples
    by seqadmin


    Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...
    03-22-2024, 06:39 AM

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