SEQanswers

Go Back   SEQanswers > Bioinformatics > Bioinformatics



Similar Threads
Thread Thread Starter Forum Replies Last Post
Assembling against a reference Tools pari_89 Bioinformatics 8 05-12-2014 05:15 AM
Assembling Paralogs park6728 Bioinformatics 1 09-01-2011 02:14 PM
de novo assembling, please help cli Bioinformatics 3 07-30-2011 04:37 AM
alignment and reference genome assembling slny Bioinformatics 3 03-16-2011 07:49 AM
454 assembling against reference genome donniemarco 454 Pyrosequencing 2 08-17-2009 07:22 AM

Reply
 
Thread Tools
Old 06-27-2013, 07:58 AM   #1
pari_89
Member
 
Location: Newcastle upon Tyne

Join Date: Apr 2013
Posts: 55
Default Assembling against a reference

Hello everyone,

I have been doing some reading about mapping and assembling against a reference and I cannot quite understand the difference? What I understand it that mapping against a reference gives alignment scores while assembling produce a set of contigs.

I have used CLCworkbench - maps reads against a reference, runMapping from Newbler and MIra to do a mapping assembly? I get a list of contigs as well.

Some sources say that mapping is not assembly. Can anyone please explain to me or give me some papers to understand this please.

Thank you.
pari_89 is offline   Reply With Quote
Old 06-27-2013, 08:24 AM   #2
swaraj
Member
 
Location: Naples, Italy

Join Date: Feb 2012
Posts: 50
Default

This should help.

http://www.ncbi.nlm.nih.gov/pubmed/21897427
swaraj is offline   Reply With Quote
Reply

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off




All times are GMT -8. The time now is 07:22 AM.


Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2019, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO