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07-17-2008, 09:47 AM
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#1 |
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Senior Member
Location: Canada Join Date: Jun 2008
Posts: 103
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SNP Allele-Frequency Determination in Pooled DNA Samples using solexa
When sequencing pooled population DNA Samples, how the relative amounts of each allele in a sample change?
After mapping the short reads, we caculate the SNP frequency(minor,major), can we use this frequency to estimate the frequency in the original sample? |
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07-19-2008, 01:21 AM
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#2 |
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Senior Member
Location: Canada Join Date: Jun 2008
Posts: 103
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anybody here give me suggestions?
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