Hi all,
I am new to the field. Here is a silly question:
For quantification of defined genomic regions (let it be genes, windows of a fixed size, etc) based on sequencing data, why do people rarely count base-pairs within the regions but rather count reads.
Could anyone shed some light on the dis/advantages for counting base-pairs/reads?
Thanks in advance
I am new to the field. Here is a silly question:
For quantification of defined genomic regions (let it be genes, windows of a fixed size, etc) based on sequencing data, why do people rarely count base-pairs within the regions but rather count reads.
Could anyone shed some light on the dis/advantages for counting base-pairs/reads?
Thanks in advance