Go Back   SEQanswers > Literature Watch

Similar Threads
Thread Thread Starter Forum Replies Last Post
ChIP-Seq: PeakAnalyzer: Genome-wide annotation of chromatin binding and modification Newsbot! Literature Watch 4 01-21-2017 12:50 AM
ChIP-Seq: MotifMap: integrative genome-wide maps of regulatory motif sites for model Newsbot! Literature Watch 0 01-03-2012 04:20 AM
ChIP-Seq: Whole-genome chromatin profiling from limited numbers of cells using nano-C Newsbot! Literature Watch 0 10-01-2011 03:30 AM
ChIP-Seq: Genome-wide profiling of chromatin signatures reveals epigenetic regulation Newsbot! Literature Watch 0 07-08-2011 03:50 AM
ChIP-Seq: High-Resolution Genome-wide Mapping of the Primary Structure of Chromatin. Newsbot! Literature Watch 0 01-19-2011 09:30 AM

Thread Tools
Old 07-14-2010, 03:00 AM   #1
RSS Posting Maniac

Join Date: Feb 2008
Posts: 1,443
Default ChIP-Seq: Genome-wide chromatin maps derived from limited numbers of hematopoietic pr

Syndicated from PubMed RSS Feeds

Related Articles Genome-wide chromatin maps derived from limited numbers of hematopoietic progenitors.

Nat Methods. 2010 Jul 11;

Authors: Adli M, Zhu J, Bernstein BE

Current methods for whole-genome mapping of protein-DNA interactions, performed by coupling chromatin immunoprecipitation with high-throughput sequencing (ChIP-seq), require large amounts of starting materials, which precludes their application to rare cell types. Here we combine a high-sensitivity ChIP assay with a new library preparation procedure to map histone modifications in as few as 10,000 cells. We used the technique to characterize mouse hematopoietic progenitors and thereby gain insight into their developmental program.

PMID: 20622861 [PubMed - as supplied by publisher]

Newsbot! is offline   Reply With Quote

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

All times are GMT -8. The time now is 10:13 AM.

Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2021, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO