Go Back   SEQanswers > Literature Watch

Similar Threads
Thread Thread Starter Forum Replies Last Post
ChIP-Seq: PeakAnalyzer: Genome-wide annotation of chromatin binding and modification Newsbot! Literature Watch 4 01-21-2017 12:50 AM
ChIP-Seq: CHROMATRA: a Galaxy tool for visualizing genome-wide chromatin signatures. Newsbot! Literature Watch 0 01-13-2012 03:30 AM
ChIP-Seq: High-resolution genome-wide in vivo footprinting of diverse transcription f Newsbot! Literature Watch 1 08-24-2011 08:45 AM
ChIP-Seq: Genome-wide profiling of chromatin signatures reveals epigenetic regulation Newsbot! Literature Watch 0 07-08-2011 03:50 AM
ChIP-Seq: Genome-wide chromatin maps derived from limited numbers of hematopoietic pr Newsbot! Literature Watch 0 07-14-2010 03:00 AM

Thread Tools
Old 01-19-2011, 09:30 AM   #1
RSS Posting Maniac

Join Date: Feb 2008
Posts: 1,443
Default ChIP-Seq: High-Resolution Genome-wide Mapping of the Primary Structure of Chromatin.

Syndicated from PubMed RSS Feeds

High-Resolution Genome-wide Mapping of the Primary Structure of Chromatin.

Cell. 2011 Jan 21;144(2):175-86

Authors: Zhang Z, Pugh BF

The genomic organization of chromatin is increasingly recognized as a key regulator of cell behavior, but deciphering its regulation mechanisms requires detailed knowledge of chromatin's primary structure-the assembly of nucleosomes throughout the genome. This Primer explains the principles for mapping and analyzing the primary organization of chromatin on a genomic scale. After introducing chromatin organization and its impact on gene regulation and human health, we then describe methods that detect nucleosome positioning and occupancy levels using chromatin immunoprecipitation in combination with deep sequencing (ChIP-Seq), a strategy that is now straightforward and cost efficient. We then explore current strategies for converting the sequence information into knowledge about chromatin, an exciting challenge for biologists and bioinformaticians.

PMID: 21241889 [PubMed - in process]

Newsbot! is offline   Reply With Quote

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

All times are GMT -8. The time now is 09:23 AM.

Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2021, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO