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  • What can we do about gene patents?

    Illumina recently announced its cancer panel. BRCA1 and BRCA2 are, of course, left out due to patents on these crucial genes involved in breast and ovarian cancers. Cancer panels provided by other institutions will probably follow suit. We are at a crucial juncture before a potential Supreme Court ruling that could seal the fate of our genes. Is there anything that we as a community can do to make a difference?

    Somewhat off the main point, but related . . . If these genes can't be included in a targeted-capture panel, can you target the reverse-complement sequence? The patent is on the gene, and the gene is on just one of the two strands - so why not just go after the other strand? Probably wouldn't fly, but I just thought I would throw that out there.

    I would like to do something, rather than just sit around and see what happens, but not quite sure what best to do. Any ideas?

    thanks,
    Justin

  • #2
    You can answer a USPTO request for comments

    The United States Patent and Trademark Office has requested comments from the public and is currently holding public hearings around the topic of genetic diagnostic testing.

    Read the Federal Register announcement giving details and instructions on how to submit your comments--you can do so by e-mail. They will become part of the public record on this matter.

    Request for Comments and Notice of Public Hearings on Genetic Diagnostic
    Testing
    (link to Federal Register announcement)


    You can PM me if you have any questions.

    Comment


    • #3
      Thanks, Joann. That is very interesting. Looks like the second of the public hearings is tomorrow (March 9), so it will be interesting to follow what comes of that.

      Justin

      Comment


      • #4
        You can answer a USPTO request for comments

        From the public hearings, there are usually transcripts/video available afterwards for review. And March 26 is the deadline for submitting additional comment by email. I aim to inspect hearings proceedings and then see what I can add in an e-mail comment that doesn't duplicate previous comments.

        Comment


        • #5
          Update

          Check your news services for digested info about important SCOTUS ruling today bearing on gene patents as finding for laws of nature not patentable.

          Comment


          • #6
            Originally posted by Joann View Post
            Check your news services for digested info about important SCOTUS ruling today bearing on gene patents as finding for laws of nature not patentable.
            Hi Joann,

            Are you referring to the ruling in the Prometheus case about blood monitoring of drug dosages? Definitely looks like a step in the right direction, although I am not sure how it affects the case against gene patents. While the Prometheus case dealt with observing and measuring a natural phenomenon occurring in humans, the gene patent case deals with the act of isolating and purifying a gene outside of humans. Thanks for the update!

            Justin

            Comment


            • #7
              Connecting the dots. Previously the DOJ wrote a very good (IMHO) amicus for the Myriad case centered on discoveries of natural law* that would invalidate gene patents. This and other amici can be found online as well as that case complainants' appeals which are headed to SCOTUS. If you can't find them, and want to look at them, let me know and I will post links here.

              *This position is also supported by other decisions rejecting patenting too far upstream in the biotech area.

              Comment


              • #8
                Latest in the BRCA gene patent case:

                Supreme Court Orders New Look at Gene Patents

                Appeals court will take another look at the case in light of the ruling in the Prometheus case. Probably will just delay a definitive decision on the matter for a while.

                Comment


                • #9
                  Time for total industry realignment. So Myriad should settle.

                  Comment


                  • #10
                    move to a country where these patents don't apply

                    Comment


                    • #11
                      Latest news involving gene patents, this time with 23andMe on a gene related to Parkinson's disease:

                      Comment


                      • #12
                        The Perils of Gene Patents

                        Interesting background and perspective on gene patents.

                        Comment


                        • #13
                          I believe there is another appeals court hearing scheduled for July in the Myriad case. I also think as previously mentioned the Ariad-Eli Lilly case is important--it looks like Eli Lilly had exceptionally good legal advice at the time they set up and engaged in their bench research and development and it held in the case that came of it-- really helps clarify the current gene patent problems now. From a different perspective, I think it is incumbent upon scientists to simply learn more about intellectual property and the role that patents (good patents and bad patents) play in helping to assemble the commercial milieu that supports product availability, or not, and to have this knowledge in their tool kits. Also I am very much in favor of less secrecy in the biological sciences--bioinformatic dissemination of information has really lifted the standards on secrecy and accessibility, in my opinion, in a very healthy way and I can only encourage these developments further.
                          Last edited by Joann; 06-15-2012, 11:28 AM. Reason: company name correction

                          Comment


                          • #14
                            Interesting article about the implications of proprietary databases of genetic variants, focusing on Myriad.

                            https://www.eshg.org/fileadmin/eshg/Downloads/EJHG_Paper_RCD_October_31_2012.pdf

                            Comment


                            • #15
                              U.S. Supreme Court agrees to hear challenge against Myriad, probably in March and rule by the end of June.

                              Comment

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