The new Globin-Zero™ Gold Kit from Epicentre effectively removes the highly abundant adult globin mRNAs and the cytoplasmic and mitochondrial rRNAs from human, mouse and rat blood RNA. The resulting Globin-Zero treated RNA is enriched for non-globin coding and non-coding RNAs for subsequent preparation of high complexity RNA-Seq libraries. The single-pass Globin-Zero process yields consistent globin and rRNA removal from both intact and partially degraded blood RNA samples
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by seqadmin
The field of epigenetics has traditionally concentrated more on DNA and how changes like methylation and phosphorylation of histones impact gene expression and regulation. However, our increased understanding of RNA modifications and their importance in cellular processes has led to a rise in epitranscriptomics research. “Epitranscriptomics brings together the concepts of epigenetics and gene expression,” explained Adrien Leger, PhD, Principal Research Scientist...-
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04-22-2024, 07:01 AM -
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by seqadmin
Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...-
Channel: Articles
04-04-2024, 04:25 PM -
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04-10-2024, 09:21 AM
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