Nieve statistical question
We have the following data:
control: 3 biological replicates
treatment 1: 2 biological replicates
treatment 2: 2 biological replicates
Using DESeq2 and running 3 separate comparisons we get:
1. ctl vs treatment 1 ~ 160 genes up-regulated
2. ctl vs treatment 2 ~ 660 genes up-regulated
3. treatment1 vs treatment 3 ~ NO genes up-regulated
So, if we compare data from 1 & 2 we get ~ 500 genes differentiially up-regulated between treatment 1 : treatment2, but none if we compare them directly (#3).
I assume this means T1 & T2 distributions are nearly identical, and differ from the control.
Correct?
Charles
We have the following data:
control: 3 biological replicates
treatment 1: 2 biological replicates
treatment 2: 2 biological replicates
Using DESeq2 and running 3 separate comparisons we get:
1. ctl vs treatment 1 ~ 160 genes up-regulated
2. ctl vs treatment 2 ~ 660 genes up-regulated
3. treatment1 vs treatment 3 ~ NO genes up-regulated
So, if we compare data from 1 & 2 we get ~ 500 genes differentiially up-regulated between treatment 1 : treatment2, but none if we compare them directly (#3).
I assume this means T1 & T2 distributions are nearly identical, and differ from the control.
Correct?
Charles
Comment