SEQanswers

Go Back   SEQanswers > Sequencing Technologies/Companies > Illumina/Solexa



Similar Threads
Thread Thread Starter Forum Replies Last Post
Drop down in Q30 on Miseq Elham1 Illumina/Solexa 10 07-20-2015 01:25 PM
How many HiSeqs still run a control lane? pmiguel Illumina/Solexa 6 04-27-2015 09:49 AM
Drop in scores after 41 cycles mvignali Illumina/Solexa 1 07-30-2010 12:08 PM
Blast threads always drop to 1 k-gun12 Bioinformatics 5 07-23-2010 06:20 AM
FastQ drop (illumina) strob Bioinformatics 2 07-14-2009 11:09 AM

Reply
 
Thread Tools
Old 10-07-2015, 12:43 AM   #1
luc
Senior Member
 
Location: US

Join Date: Dec 2010
Posts: 429
Default drop the Hiseqs - get an X10 instead

In a new episode of Illumina's arbitrary gaming of the sequencing market fight for scientific progress, it opens the X10s and X5s for the resequencing of all genomes:
http://www.businesswire.com/news/hom.../#.VhTI1JbJUwB

Theoretically, this leaves RNA-seq for the Hiseqs.
luc is offline   Reply With Quote
Old 10-07-2015, 10:41 AM   #2
AllSeq
Registered Vendor
 
Location: San Diego, CA

Join Date: Oct 2013
Posts: 138
Default

Quote:
Originally Posted by luc View Post
In a new episode of Illumina's arbitrary gaming of the sequencing market fight for scientific progress, it opens the X10s and X5s for the resequencing of all genomes:
http://www.businesswire.com/news/hom.../#.VhTI1JbJUwB

Theoretically, this leaves RNA-seq for the Hiseqs.
Not quite. Illumina is still (arbitrarily) limiting the HiSeq X to "large" genomes. They're trying to encourage (accommodate) large projects sequencing crop species, livestock, model mammalian species, etc. Smaller genomes need not apply.
__________________
AllSeq - The Sequencing Marketplace
info@AllSeq.com
www.AllSeq.com
AllSeq is offline   Reply With Quote
Old 10-07-2015, 10:59 AM   #3
luc
Senior Member
 
Location: US

Join Date: Dec 2010
Posts: 429
Default

The press release says:
" ... will allow for market expansion and population-scale sequencing of non-human species in a variety of markets, including plants and livestock in agricultural research and model organisms in pharmaceutical research. Previously, it has been cost prohibitive to sequence non-human genomes at high coverage. ..."
This can be anything as far as I can see. Illumina is not going to check on what is being sequenced anyhow.
luc is offline   Reply With Quote
Old 10-07-2015, 11:03 AM   #4
AllSeq
Registered Vendor
 
Location: San Diego, CA

Join Date: Oct 2013
Posts: 138
Default

I can't say what Illumina will and won't check, but based on what info we've been able to gather (customer conversations, analyst questions), Illumina definitely intends this to be for large genomes only. That said, I'm not sure how useful such a large platform would be for small genomes - it would take a LOT of samples to fill out a run. But maybe there are ultra-large small genome projects just waiting for this opportunity.
__________________
AllSeq - The Sequencing Marketplace
info@AllSeq.com
www.AllSeq.com
AllSeq is offline   Reply With Quote
Old 10-07-2015, 11:13 AM   #5
GenoMax
Senior Member
 
Location: East Coast USA

Join Date: Feb 2008
Posts: 7,014
Default

@AllSeq: Analysis of HiSeq X data happens on the attached computer (or in BaseSpace) so this "large" genome restriction could be enforced "inline"?

It sounds to me like they are opening HiSeq X up for large plant/animal biotech companies that previously could not use HiSeq X. They probably have tens of thousands of samples that could be multiplexed.
GenoMax is offline   Reply With Quote
Old 10-07-2015, 11:48 AM   #6
AllSeq
Registered Vendor
 
Location: San Diego, CA

Join Date: Oct 2013
Posts: 138
Default

@GenoMax: We don't use the instruments ourselves, so I'm not really sure about the workflow and exactly how Illumina monitors what's going on. We've heard of a couple of examples of providers 'bending the rules', but it always seems to be with the permission of Illumina. We've never heard of a full-blown 'breach of contract'. Not sure if that elicits a tap on the shoulder from the local FAS or perhaps a friendly call from Jay Flatley? ;-)

And, yes, I think they're definitely looking to serve the PAG market. It's pretty clear from their quarterly reports (and from what we see on the Sequencing Marketplace) that there's quite a bit of excess X capacity out there. Illumina would love to fill that up (and entice new markets to purchase X's).
__________________
AllSeq - The Sequencing Marketplace
info@AllSeq.com
www.AllSeq.com
AllSeq is offline   Reply With Quote
Reply

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off




All times are GMT -8. The time now is 07:09 AM.


Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO