Hello all,
I have >150 sorted alignment bam files (>50G) by applying bwa, do I have to merge them into one single file before any further analysis?
If I just run SNP calling on each of the bam file and merge them together, how about the duplicates? It might be different with the result coming from a big single bam file.
Thanks in advance for any help.
I have >150 sorted alignment bam files (>50G) by applying bwa, do I have to merge them into one single file before any further analysis?
If I just run SNP calling on each of the bam file and merge them together, how about the duplicates? It might be different with the result coming from a big single bam file.
Thanks in advance for any help.
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