Hi,
I am working on identifying variants in affected individuals the we exome sequenced. Going through the variants after filtering out variants in the 1000 Genomes project, dbSNP and ESP6500, I was wondering if there is a list out there for variants in genes that we need to not consider for follow up as they always appear in every sequencing project such as the MUC genes. Is there such a list or a list of hypervariable genes publically available that can be used to remove variants in genes reported in these lists?
thanks
I am working on identifying variants in affected individuals the we exome sequenced. Going through the variants after filtering out variants in the 1000 Genomes project, dbSNP and ESP6500, I was wondering if there is a list out there for variants in genes that we need to not consider for follow up as they always appear in every sequencing project such as the MUC genes. Is there such a list or a list of hypervariable genes publically available that can be used to remove variants in genes reported in these lists?
thanks
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