SEQanswers

Go Back   SEQanswers > Bioinformatics > Bioinformatics



Similar Threads
Thread Thread Starter Forum Replies Last Post
Somatic Mutations in dbSNP qqcandy Bioinformatics 14 07-27-2015 02:34 PM
Help with Varscan somatic bug report and interpret mpileup2cns result edge Bioinformatics 4 02-25-2015 01:43 AM
Somatic mutation analysis WaitingNail Bioinformatics 1 09-02-2013 07:40 PM
Somatic mutations in dbsnp--constant 5% LiLin Bioinformatics 0 05-16-2013 01:07 AM

Reply
 
Thread Tools
Old 04-15-2014, 01:02 AM   #1
david.tamborero
Member
 
Location: spain

Join Date: Feb 2011
Posts: 60
Default interpret a somatic mutation labelled in dbsnp

Hi,

I am analysing somatic mutations that -theoretically- have been already filtered for SNPs -I'm not involved in the mutation pipeline-; the point is that by checking them by my own I've found that some of them are within dbSNP; but I am not able to know the origin of their annotation, since the "SAO" flag states 'unknown' and the entry does not give info about allele frequency, etc (see e.g. rs140934881). By the way, in most of the cases I do not find there dbSNP entries in other databases as 1K genomes or ESP6500.

Any suggestion of what I have to do? Can I consider them as true somatic?

many thanks!
--david
david.tamborero is offline   Reply With Quote
Reply

Tags
dbsnp, polimorphism, somatic mutations

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off




All times are GMT -8. The time now is 01:40 AM.


Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO