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Old 02-24-2011, 11:37 PM   #1
pinki999
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Location: Germany

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Default Length bias correction for biological replicates

Hello,

I recently read a paper: "Length bias correction for RNA-seq data in Gene set analyses". In this paper authors state that "This study is based on RNA-seq experiments with only technical replicates."

I am a newbie to NGS and am dealing with biological replicates. I am analyzing the data to find differentially expressed transcripts and then carry out gene set analyses. My question is: Can I apply this method for the biological replicates? or Are there any other correction methods for biological replicates?

Regards,
Pinki
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