Go Back   SEQanswers > Applications Forums > RNA Sequencing

Similar Threads
Thread Thread Starter Forum Replies Last Post
quantification of transcript level bogdan RNA Sequencing 6 06-19-2018 08:04 AM
Postdoctoral Fellow: Algorithms for Long Read Transcript Quantification JMG Academic/Non-Profit Jobs 0 08-16-2017 01:34 AM
Coverage of a transcript and accuracy of DE bruce01 General 0 01-08-2014 08:03 AM
ABRF Study to compare accuracy and reproducibility of DNA/RNA quantification methods sslevine Sample Prep / Library Generation 0 11-22-2013 12:09 PM
SOLiD Accuracy Enhancement Tool (SAET) multicore and ref genome size questions KevinLam Bioinformatics 11 08-31-2012 08:54 AM

Thread Tools
Old 06-05-2018, 10:31 AM   #1
Junior Member
Location: BioTuring

Join Date: Apr 2015
Posts: 2
Default NORA: A tool for transcript quantification where accuracy matters

NORA: Accuracy approximates RSEM+bowtie2 with the speed of Kallisto and Salmon


We introduce Nora, a tool for transcript quantification where accuracy matters. Nora is much more accurate than Hera, an algorithm that we released last year (Hera obtained the best ranking in the latest round of SMC-RNA DREAM challenge). Nora also outputs accurate read alignments in bam format, while time and memory consumption is similar to pseudo-alignment approaches’.

Nora source code is written in C using the linux kernel coding style . The compiled package is tiny: 262 KB, and can be installed on most macOS and linux distributions without dependencies. For now, Nora’s binary package is not yet released for public. To use Nora, you need to get an invitation.

Benchmark Data

We benchmarked Nora and other transcript quantification tools (Hera, Kallisto, Salmon, RSEM+Bowtie2) using 20 simulated data sets generated from Kallisto paper (using this script), and the most recent benchmark data from SMC-RNA DREAM challenge.

Benchmark Results

Please visit the homepage of Nora for full of the benchmark tables.

Try Nora

Nora will soon be available for both Linux and Mac in a command line interface, a lite app version, a workstation platform, and a cloud application. If you are interested in Nora and want to give it a try, just let us know through [email protected].

Thank you!
My blog: BioTuring's blog
Nora: A tool for transcript quantification where accuracy matters
BioVinci: Graphing data troubles you? Data visualization made easy with BioVinci
BioTuring: We develop state-of-the-art bioinformatics algorithms to extract information from next-generation sequencing data.

Last edited by ptdtan; 06-07-2018 at 09:24 PM. Reason: I want to clarify how Nora performs compared to other tools.
ptdtan is offline   Reply With Quote
Old 06-18-2018, 11:56 PM   #2
Junior Member
Location: S-120 Ground Floor, Lane No 3, New Rajapuri, Dwarka Sector-3

Join Date: Jan 2018
Posts: 1

Thanks For This Information, Really Helpful!
jdmwebtechnologies is offline   Reply With Quote

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

All times are GMT -8. The time now is 04:35 PM.

Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2018, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO