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Old 04-03-2013, 01:31 AM   #1
maimaiti2008
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Default How likely is one region to be sequenced as two duplicates due to assembly error?

If a assembly is based on a wrong reference genome where a single gene is assembled as a tandem duplicate, how likely is it for the new assembly to have the same error in this region?
Thanks!
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Old 04-03-2013, 04:36 PM   #2
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Does anyone have any ideas?
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Old 04-04-2013, 06:08 AM   #3
dpryan
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There's no theoretical single answer to your question. It would depend on how the assembler is implemented (and likely the particulars of the false tandem duplication).
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