Hi all,
Now I have a DNase-data set (paired-end) and I wanted to get the cleavage profile for each genome base. Here is my question: suppose mate 1 read of a fragment aligns to genome position 1 - 35 and mate 2 read of the same fragment aligns to genome position 60 - 94. Should I think there is one cut event for both position 1 and position 94, or only position 1?
Thanks!
Now I have a DNase-data set (paired-end) and I wanted to get the cleavage profile for each genome base. Here is my question: suppose mate 1 read of a fragment aligns to genome position 1 - 35 and mate 2 read of the same fragment aligns to genome position 60 - 94. Should I think there is one cut event for both position 1 and position 94, or only position 1?
Thanks!