|
|
|
|
|||||||
Similar Threads
|
||||
| Thread | Thread Starter | Forum | Replies | Last Post |
| Gene Set Enrichment Analysis | uqfgaiti | Bioinformatics | 1 | 07-12-2014 04:14 PM |
| SeqGSEA: Gene Set Enrichment Analysis of RNA-Seq Data | Xi Wang | RNA Sequencing | 20 | 05-26-2014 06:28 AM |
| SeqGSEA: Gene Set Enrichment Analysis of RNA-Seq Data | Xi Wang | Bioinformatics | 3 | 10-01-2013 08:44 AM |
| Gene set enrichment analysis of RNA-Seq data | jel4h | Bioinformatics | 1 | 06-21-2012 05:25 AM |
 |
|
|
Thread Tools |
12-26-2017, 05:03 AM
|
#1 |
|
Member
Location: Switzerland Join Date: Aug 2009
Posts: 30
|
Background set for GO enrichment analysis
Hello,
I determined that out of ~70'000 transcripts, ~15'000 are spatially regulated (I used the LRT method in DESeq2). The patterns of these 15'000 transcripts clustered into 15 groups. I would like now to perform a GO gene set enrichment analysis for the transcripts in each cluster. It seems more logical to me that my "background" annotation will comprise the 15'000 transcripts, not the 70'000. Is it correct? Many thanks ! Yvan |
|
|
|
01-10-2018, 12:41 PM
|
#2 |
|
I like code
Location: San Diego, CA, USA Join Date: Sep 2009
Posts: 438
|
I'd agree with that whereas if you were interested in GO enrichment of the 15,000 genes you'd then use the 70,000 as the background.
__________________
/* Shawn Driscoll, Gene Expression Laboratory, Pfaff Salk Institute for Biological Studies, La Jolla, CA, USA */ |
|
|
|
|
| Tags |
| go analysis, gsea, rna-seq |
| Thread Tools | |
|
|
