Just wondering, would anyone be able to recommend software for predicting whether mutations will introduce cryptic splice sites into genes? I've come across several software packages that look like they could do this (e.g. Human Splicing Finder, Spliceman, NetGene2) but I have no idea which, if any of these are worth using for mutation analysis.
Are any of these (or others) worth using to find pathogenic mutations, or is cryptic splice site prediction still too inaccurate to be of much value for this kind of thing?
Are any of these (or others) worth using to find pathogenic mutations, or is cryptic splice site prediction still too inaccurate to be of much value for this kind of thing?