Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • Oxford Nanopore

    For originality this is the first 3rd gene sequencing by destruction. An exonuclease feeds cleaved bases into a modified hemolysin, while the potential is monitored. According to Oxford modified hemolysin (more specifically the cyclodextrin modification) interacts differently with each base resulting in a different potential drop allowing the base discrimination.

    Pros: Look ma, no label. No amplification, no label, this is a close to pure DNA readout as one can imagine (might also do methylated DNA)
    Con: Lipid bilayers are notoriously fluid causing motion in the pore. Manufacturing and kitting lipid bilayers as consumables, logistical nightmare. This is a great technology for a single pore, but pore arrays for this readout and the bilayer will be another large hurdle. Commercialization will be VERY challenging, perhaps this would be better as a service?

    I will be interested to see how they progress.

    Video here:
    http://www.nanoporetech.com/sequences/

Latest Articles

Collapse

  • seqadmin
    Techniques and Challenges in Conservation Genomics
    by seqadmin



    The field of conservation genomics centers on applying genomics technologies in support of conservation efforts and the preservation of biodiversity. This article features interviews with two researchers who showcase their innovative work and highlight the current state and future of conservation genomics.

    Avian Conservation
    Matthew DeSaix, a recent doctoral graduate from Kristen Ruegg’s lab at The University of Colorado, shared that most of his research...
    03-08-2024, 10:41 AM
  • seqadmin
    The Impact of AI in Genomic Medicine
    by seqadmin



    Artificial intelligence (AI) has evolved from a futuristic vision to a mainstream technology, highlighted by the introduction of tools like OpenAI's ChatGPT and Google's Gemini. In recent years, AI has become increasingly integrated into the field of genomics. This integration has enabled new scientific discoveries while simultaneously raising important ethical questions1. Interviews with two researchers at the center of this intersection provide insightful perspectives into...
    02-26-2024, 02:07 PM

ad_right_rmr

Collapse

News

Collapse

Topics Statistics Last Post
Started by seqadmin, 03-14-2024, 06:13 AM
0 responses
32 views
0 likes
Last Post seqadmin  
Started by seqadmin, 03-08-2024, 08:03 AM
0 responses
71 views
0 likes
Last Post seqadmin  
Started by seqadmin, 03-07-2024, 08:13 AM
0 responses
80 views
0 likes
Last Post seqadmin  
Started by seqadmin, 03-06-2024, 09:51 AM
0 responses
68 views
0 likes
Last Post seqadmin  
Working...
X