Hi,
We'd like to convert hg19 coordinates to Broad's b37 reference coordinates. For example UCSC's "Known Genes" annotations can only be retrieved in hg19 (or lower) coordinates. b37 sequence differs from hg19 in particular on chrY and the mitochondrial genome.
I've done some searching around here and inquired with various other resources. Liftover seems like a useful tool but I haven't been able to locate a hg19tob37 chain file.
Can anyone recommend a good way forward?
Many thanks in advance,
Lao
We'd like to convert hg19 coordinates to Broad's b37 reference coordinates. For example UCSC's "Known Genes" annotations can only be retrieved in hg19 (or lower) coordinates. b37 sequence differs from hg19 in particular on chrY and the mitochondrial genome.
I've done some searching around here and inquired with various other resources. Liftover seems like a useful tool but I haven't been able to locate a hg19tob37 chain file.
Can anyone recommend a good way forward?
Many thanks in advance,
Lao
Comment