SEQanswers

Go Back   SEQanswers > Literature Watch



Similar Threads
Thread Thread Starter Forum Replies Last Post
RNA-Seq: RNA-Seq Analysis of Gene Expression and Alternative Splicing by Double-Rando Newsbot! Literature Watch 0 03-03-2011 02:00 AM
Test datasets for judging RNA-seq alternative splicing detection tools acnoll RNA Sequencing 0 02-10-2010 07:33 AM
Alternative splicing detection using RNA-seq jiwu2573 Bioinformatics 9 02-05-2010 07:56 PM
Alternative splicing detection using RNA-seq jiwu2573 RNA Sequencing 0 01-24-2010 08:06 PM
A Statistical Method for the Detection of Alternative Splicing Using RNA-Seq krobison Literature Watch 0 01-11-2010 10:09 AM

Reply
 
Thread Tools
Old 01-10-2012, 04:00 AM   #1
Newsbot!
RSS Posting Maniac
 

Join Date: Feb 2008
Posts: 1,443
Default RNA-Seq: Detection, annotation and visualization of alternative splicing from RNA-Seq

Syndicated from PubMed RSS Feeds

Detection, annotation and visualization of alternative splicing from RNA-Seq data with SplicingViewer.

Genomics. 2011 Dec 28;

Authors: Liu Q, Chen C, Shen E, Zhao F, Sun Z, Wu J

Abstract
Alternative splicing is a crucial mechanism by which diverse gene products can be generated from a limited number of genes, and is thought to be involved in complex orchestration of eukaryotic gene expression. Next-generation sequencing technologies, with reduced time and cost, provide unprecedented opportunities for deep interrogation of alternative splicing at the genome-wide scale. In this study, an integrated software SplicingViewer has been developed for unambiguous detection, annotation and visualization of splice junctions and alternative splicing events from RNA-Seq data. Specifically, it allows easy identification and characterization of splice junctions, and holds a versatile computational pipeline for in-depth annotation and classification of alternative splicing with different patterns. Moreover, it provides a user-friendly environment in which an alternative splicing landscape can be displayed in a straightforward and flexible manner. In conclusion, SplicingViewer can be widely used for studying alternative splicing easily and efficiently. SplicingViewer can be freely accessed at http://bioinformatics.zj.cn/splicingviewer.


PMID: 22226708 [PubMed - as supplied by publisher]



More...
Newsbot! is offline   Reply With Quote
Reply

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off




All times are GMT -8. The time now is 05:15 PM.


Powered by vBulletin® Version 3.8.9
Copyright ©2000 - 2020, vBulletin Solutions, Inc.
Single Sign On provided by vBSSO