Dear Bioinformatics community,
DNase-seq has been used to measure chromatin accessibility in a given
tissue or cell type on a genome-wide scale. In addition to DNaseI
hypersensitivite sites (DHSs), short regions of protected nucleotides
known as footprints can be detected, indicating transcription factor
binding ocuppancy events.
DNaseR, a new package for DNase I footprinting analysis of DNase-seq
data has been released in the current version Bioconductor. Devel
version is at: http://bioconductor.org/packages/2.1...ml/DNaseR.html
DNaseR aims to detect protein binding footprints in DNase-seq data
from reads in BAM standard aligment format.
Best regards,
Pedro Madrigal
Research Associate
Wellcome Trust Sanger Institute
Wellcome Trust Genome
CampusHinxton,
Cambridge, CB10 1SAUK
DNase-seq has been used to measure chromatin accessibility in a given
tissue or cell type on a genome-wide scale. In addition to DNaseI
hypersensitivite sites (DHSs), short regions of protected nucleotides
known as footprints can be detected, indicating transcription factor
binding ocuppancy events.
DNaseR, a new package for DNase I footprinting analysis of DNase-seq
data has been released in the current version Bioconductor. Devel
version is at: http://bioconductor.org/packages/2.1...ml/DNaseR.html
DNaseR aims to detect protein binding footprints in DNase-seq data
from reads in BAM standard aligment format.
Best regards,
Pedro Madrigal
Research Associate
Wellcome Trust Sanger Institute
Wellcome Trust Genome
CampusHinxton,
Cambridge, CB10 1SAUK