There has been some discussion on here regarding MHC genotyping using next-gen, so I thought I would share our recent contribution:
The rational can be applied to genotyping any multi-template amplicon e.g. sequenced micro-sats, and helps to deal with cross-sample contamination (or stutter in micros) that is common in such approaches.
Cheers,
J
The rational can be applied to genotyping any multi-template amplicon e.g. sequenced micro-sats, and helps to deal with cross-sample contamination (or stutter in micros) that is common in such approaches.
Cheers,
J
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