Hi,
I am wondering what the general consensus is on SNP/Indel detection from resequencing data generated by homopolymer error-prone platforms like 454 and Ion torrent?
Off the top of my head I theorize that SNP detection should generally not be a problem but analysis of Indels would be. Am I correct in this assumption?
Are there any general anlysis approaches that attempt to compensate for these problems?
Thanks in advance.
I am wondering what the general consensus is on SNP/Indel detection from resequencing data generated by homopolymer error-prone platforms like 454 and Ion torrent?
Off the top of my head I theorize that SNP detection should generally not be a problem but analysis of Indels would be. Am I correct in this assumption?
Are there any general anlysis approaches that attempt to compensate for these problems?
Thanks in advance.
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