Hi, I'm new to the next-generation sequencing data and got confused with some concepts. Could anyone give me some help?
Take the bam files of 1000 genome data from pilot 3 as an example, I was able to use samtools to view or get consensus. But -c in pileup only give a consensus sequence. Is there a way to make consensus genotype call, including homozygous and heterozygous polymorphisms?
Thanks a lot in advance for any hint!
Cindy
Take the bam files of 1000 genome data from pilot 3 as an example, I was able to use samtools to view or get consensus. But -c in pileup only give a consensus sequence. Is there a way to make consensus genotype call, including homozygous and heterozygous polymorphisms?
Thanks a lot in advance for any hint!
Cindy
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