POSTDOC: Comparative genomics of bacterial pathogens (University of Pittsburgh)

eswright · 02-16-2021, 09:20 AM

The Wright Lab (http://wrightlabscience.com) is seeking a postdoctoral associate to lead a project aimed at analyzing tens of thousands of genomes belonging to bacterial pathogens. The successful candidate will apply evolutionary principles to uncover determinants of pathogenicity and antibiotic resistance across multiple species. The project will involve applying cutting-edge algorithms to a dataset consisting of over ten thousand pathogens with known genotypes and phenotypes. Analyses include detecting (1) HGT, (2) genotypes underlying phenotypes, (3) new non-coding RNAs, (4) selection pressure (dN/dS), and (5) compensatory mutations. This research provides the opportunity to apply tools at the forefront of bioinformatics to tackle infectious diseases in the clinic.

The Wright Lab is a multi-disciplinary hybrid wet/dry lab at the University of Pittsburgh. We are part of a broader effort to make the University of Pittsburgh a leader in applying evolution to the improvement of medicine (https://www.cebam.pitt.edu). The university consistently ranks in the top 10 nationally for biomedical research funding.

QUALIFICATIONS: Qualifications for this position include a PhD in science or engineering and the motivation to learn new skills.

TO APPLY: Please email applications (including cover letter and curriculum vitae) to Dr. Erik Wright (eswright@pitt.edu). The position starts as early as May 2021.

Erik Wright
Assistant Professor
Department of Biomedical Informatics
University of Pittsburgh, School of Medicine

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02-16-2021, 09:20 AM	#1
eswright Junior Member Location: Pittsburgh, PA Join Date: Nov 2018 Posts: 2	POSTDOC: Comparative genomics of bacterial pathogens (University of Pittsburgh) The Wright Lab (http://wrightlabscience.com) is seeking a postdoctoral associate to lead a project aimed at analyzing tens of thousands of genomes belonging to bacterial pathogens. The successful candidate will apply evolutionary principles to uncover determinants of pathogenicity and antibiotic resistance across multiple species. The project will involve applying cutting-edge algorithms to a dataset consisting of over ten thousand pathogens with known genotypes and phenotypes. Analyses include detecting (1) HGT, (2) genotypes underlying phenotypes, (3) new non-coding RNAs, (4) selection pressure (dN/dS), and (5) compensatory mutations. This research provides the opportunity to apply tools at the forefront of bioinformatics to tackle infectious diseases in the clinic. The Wright Lab is a multi-disciplinary hybrid wet/dry lab at the University of Pittsburgh. We are part of a broader effort to make the University of Pittsburgh a leader in applying evolution to the improvement of medicine (https://www.cebam.pitt.edu). The university consistently ranks in the top 10 nationally for biomedical research funding. QUALIFICATIONS: Qualifications for this position include a PhD in science or engineering and the motivation to learn new skills. TO APPLY: Please email applications (including cover letter and curriculum vitae) to Dr. Erik Wright (eswright@pitt.edu). The position starts as early as May 2021. Erik Wright Assistant Professor Department of Biomedical Informatics University of Pittsburgh, School of Medicine