Hi all,
I have two RNA-Seq samples (normal and treatment) but neither has replicates. In such a case one option is to apply edgeR with Poisson model on our data. But I know that the latest edgeR can do a better job and somehow estimate the biological variation. Unfortunately, I do not know exactly how to implement this. Could anybody help me for this?
Similar questions have been discussed here:
I have two RNA-Seq samples (normal and treatment) but neither has replicates. In such a case one option is to apply edgeR with Poisson model on our data. But I know that the latest edgeR can do a better job and somehow estimate the biological variation. Unfortunately, I do not know exactly how to implement this. Could anybody help me for this?
Similar questions have been discussed here:
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