Hi All,
I am designing an experiment to perform exome sequencing on 20 affected with their parents (trios) for detecting de novo mutations. I would like to perform a power calculation to see if I have any power in detecting de novo variant using 20 families. Any idea how to do this?
Thanks in advance
I am designing an experiment to perform exome sequencing on 20 affected with their parents (trios) for detecting de novo mutations. I would like to perform a power calculation to see if I have any power in detecting de novo variant using 20 families. Any idea how to do this?
Thanks in advance