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  • Producing associated gene lists.......?

    Does anyone know the best way to produce a list of genes (official gene ID preferably) that have the same associated function.

    for example i want to get a comprehensive list of official gene IDs for genes known to be cytokines. (in human)

    I assume I would need to find a broad GO-term that would include all cytokines, but I don't know how to produce a list which includes the official gene ID only.

    many thanks

  • #2
    Get these files : gene2go and gene_info from NCBI

    You can use these commands from command line...
    wget -nc ftp://ftp.ncbi.nlm.nih.gov/gene/DATA/gene2go.gz
    wget -nc ftp://ftp.ncbi.nlm.nih.gov/gene/DATA/gene_info.gz

    Uncompress them using "gzip -d filename.gz".

    gene2go has the id to goterm
    gene_info has the id to gene name.

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    • #3
      NCBI could be helpful. Enter "gene" next to the search bar and search "cytokine", narrow down your query by clicking on "Homo sapiens"/ whatever species you're using in the sidebar after completing your search. From there you can click on the genes of interest and create a txt file with the information you want to download. Is this helpful at all/what you were looking for?

      EDIT: Ah, previous poster beat me to the punch .

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      • #4
        Search for cytokine at: http://www.proteinatlas.org/ You should be able to download a tab delimited list from the results.

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        • #5
          That's great, thank you all

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