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Can one determine the genome-wide coverage of an individual genome deposited in the NCBI SRA database?
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Not unless you align the data. You could calculate theoretical fold representation (based on total number of bases/genome size in bp) but that may not mean much. -
Thanks, GenoMax. Is there a correlation between low genome coverage and the number of genomic gaps one sees in the alignment with a reference genome? I am trying to make sure that I look at genome-wide coverages of 10 or greater.Comment
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