There's a company in San Diego called Azco Biotech acting as sales representative for Dover. I've read that the Broad has one, although they say that it's not in use for production sequencing. Is this well-intended system still commercially viable? Does anyone want one? It would seem that technology has moved on (e.g., Ion Torrent).
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Rubenken: Thanks for posting. The Polonator is still commercially available, but despite its low upfront and recurring cost, its throughput has lagged behind that of the two major players. That said, we have not been idle, but have had our heads down working to substantially increase its performance. We will shortly be providing an update on our progress, but I expect that we will do that via Julia Karow of In Sequence. Stay tuned.
Kevin
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Proteins are often described as the workhorses of the cell, and identifying their sequences is key to understanding their role in biological processes and disease. Currently, the most common technique used to determine protein sequences is mass spectrometry. While still a valuable tool, mass spectrometry faces several limitations and requires a highly experienced scientist familiar with the equipment to operate it. Additionally, other proteomic methods, like affinity assays, are constrained...-
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Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...-
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