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Using Alta-Cyclic, which the CSHL researchers described online in Nature Methods this month, they were able to increase the number of accurate 78-base reads in a run from 5 percent to 22 percent. These reads, they say, may allow them to assemble complex eukaryotic genomes de novo.
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Using Alta-Cyclic, which the CSHL researchers described online in Nature Methods this month, they were able to increase the number of accurate 78-base reads in a run from 5 percent to 22 percent. These reads, they say, may allow them to assemble complex eukaryotic genomes de novo.
More...