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  • the strength of the TF binding

    Hi all,

    I have set of transcription factors and their targets , I need to measure the strength of the TF binding

    Iam asking, I have to calculate position weight matrix (PWMS) to measure the strength

    is there another way to do that

    Thanks

  • #2
    Strength is a vague word and probably not applicable to sequence-based data. A PWM is a reasonable and traditional way to display some aspects of nucleotide preference, barring combinatorial non-linearity.
    Providing nextRAD genotyping and PacBio sequencing services. http://snpsaurus.com

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