Seqanswers Leaderboard Ad

Collapse

Announcement

Collapse
No announcement yet.
X
 
  • Filter
  • Time
  • Show
Clear All
new posts

  • An inside look at Pacific Biosciences technologies...

    The New York Times has a good article on the current technology in use at Pacific Biosciences in Menlo Park.



    S.M.R.T. sequencing (Single Molecule Real Time) Sounds like 454 on steroids. Instead of a "picotiter plate" and pyrophosphate detection, these guys are using a "zero mode waveguide" and phospho-linked fluors.

    All I can think of is that old Simpson's episode...


  • #2
    Amazing stuff! The technology backgrounder is a good document for getting up to speed with SMRT. http://www.pacificbiosciences.com/as...ckgrounder.pdf

    A press release to GenomeWeb today reveals that the machine will be available (if one is optimistic) in 2010. http://www.genomeweb.com/issues/news/144976-1.html

    Comment


    • #3
      Here is a link to one of their very recent publications...

      Comment


      • #4
        Here's a link to their animation explaining the process.

        Comment


        • #5
          Thanks for the "unbiased" promotion of PacBio.

          (Note: It might be a good idea to put a disclaimer when you post that you work for them similar to the press releases from the marketing team of companies anticipating to go public.)

          Comment


          • #6
            Originally posted by NextGenSeq View Post
            Thanks for the "unbiased" promotion of PacBio.

            (Note: It might be a good idea to put a disclaimer when you post that you work for them similar to the press releases from the marketing team of companies anticipating to go public.)
            Hey there...I assume you're talking to me. This disclaimer has been there since the day I started at PB, and this thread was posted almost a year before I joined.

            Not sure why you keep bringing it up...I've been as open as possible since day one, and if you'd checked the date on this thread before posting what I feel is a pretty snide comment, you'd know that.

            As I said the last time you brought this up, if you would like to start a dialog about my day-job employer and how that may or may not affect the unbiased nature of the site...please do so in the Site Feedback forum and I'll answer any question and consider all opinions.

            Comment

            Latest Articles

            Collapse

            • seqadmin
              Strategies for Sequencing Challenging Samples
              by seqadmin


              Despite advancements in sequencing platforms and related sample preparation technologies, certain sample types continue to present significant challenges that can compromise sequencing results. Pedro Echave, Senior Manager of the Global Business Segment at Revvity, explained that the success of a sequencing experiment ultimately depends on the amount and integrity of the nucleic acid template (RNA or DNA) obtained from a sample. “The better the quality of the nucleic acid isolated...
              03-22-2024, 06:39 AM
            • seqadmin
              Techniques and Challenges in Conservation Genomics
              by seqadmin



              The field of conservation genomics centers on applying genomics technologies in support of conservation efforts and the preservation of biodiversity. This article features interviews with two researchers who showcase their innovative work and highlight the current state and future of conservation genomics.

              Avian Conservation
              Matthew DeSaix, a recent doctoral graduate from Kristen Ruegg’s lab at The University of Colorado, shared that most of his research...
              03-08-2024, 10:41 AM

            ad_right_rmr

            Collapse

            News

            Collapse

            Topics Statistics Last Post
            Started by seqadmin, Yesterday, 06:37 PM
            0 responses
            8 views
            0 likes
            Last Post seqadmin  
            Started by seqadmin, Yesterday, 06:07 PM
            0 responses
            8 views
            0 likes
            Last Post seqadmin  
            Started by seqadmin, 03-22-2024, 10:03 AM
            0 responses
            49 views
            0 likes
            Last Post seqadmin  
            Started by seqadmin, 03-21-2024, 07:32 AM
            0 responses
            66 views
            0 likes
            Last Post seqadmin  
            Working...
            X