Hi,
Can anyone recommend software particularly suited for very low frequency indel detection as might be applied to ultra-deep targeted sequencing (UDT-seq) datasets where coverage exceeds 1000x? Choices seem limited. Am getting the impression scripting around samtools mpileup output might be the most robust strategy. Any thoughts anyone?
Many thanks.
Can anyone recommend software particularly suited for very low frequency indel detection as might be applied to ultra-deep targeted sequencing (UDT-seq) datasets where coverage exceeds 1000x? Choices seem limited. Am getting the impression scripting around samtools mpileup output might be the most robust strategy. Any thoughts anyone?
Many thanks.
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