I've asked this before but I'm wondering if anyone has any new information or experience! I've gotten variable answers from Covaris tech support, different tech support people for our Apollo robot, and Illumina. As usual, the answer seems to be that we need to have tons of extra sample to test different Covaris settings on, and I just don't have that option.
Since cDNA is already shorter than genomic DNA, do the Covaris settings have to be adjusted to end up with properly sized DNA? I'm trying to end up with a peak ~220 bp.
Since cDNA is already shorter than genomic DNA, do the Covaris settings have to be adjusted to end up with properly sized DNA? I'm trying to end up with a peak ~220 bp.
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